Contraindicated. CYP3A4 is chargeable for the formation and elimination of cariprazine's Energetic metabolites. The outcome of CYP3A4 inducers on cariprazine publicity hasn't been evaluated as well as the Web influence is unclear.pentobarbital will reduce the extent or effect of fosaprepitant by impacting hepatic/intestinal enzyme CYP3A4 metabolism
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